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KMID : 0964020090090010053
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Journal of the Korean Liver Cancer Study Group
2009 Volume.9 No. 1 p.53 ~ p.58
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Treatment of Massive Hepatocellular Carcinoma with Portal Vein Invasion
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Kwon Jung-Hyun
Chun Ho-Jong
Bae Si-Hyun
Yoon Seung-Kew
Kim Jin-Dong
Woo Hyun-Young
Choi Jong-Young
Lee Young-Jun
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Abstract
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A 52 year-old-man patient was admitted for evaluation of hepatic mass which was detected on screening ultrasonography.
His abdominal CT showed a massive infiltrating mass in left hepatic lobe and another 2.4 cm nodule in S6 of Rt. Hepatic lobe with arterial enhancement and rapid wash out underlying liver cirrhosis. Also, low density tumor thrombus are filled in Lt. portal vein and extended into main portal vein. He was finally diagnosed HCC (UICC stage IVa) with liver cirrhosis (Child-Pugh class A) and hepatitis B. With the four times of trasnarterial chemo-lipiodolization and seven times of ntraarterial infusion chemotherapy for huge mass and one time Radiofrequency ablation (RFA) for daughter nodule, his HCC showed no stain in hepatic angiogram at nine month from initial diagnosis. After additional eight times of intra-arterial infusion chemotherapy, new small nodule developed in S6 and was ablated with RFA. At eighteen months after initial diagnosis, he shows no viable lesion on the imaging study and tumor markers are normalized.
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KEYWORD
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Massive hepatocellular carcinoma, Transarterial chemo-Lipiodolization, Intra-arterial infusion chemotherapy
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